Vibrating Mattress Helps Clear Alzheimer's Protein From the Brain

A vibrating mattress combined with two pills that release nitric oxide enhanced the brain's ability to clear an Alzheimer's-related protein. According to New Scientist, the experiment "caused the brain's blood vessels to swell and constrict more strongly, which enhanced the glymphatic system's clearance of [the protein]." From the report: [Kesa Kiviniemi at the University of Oulu in Finland] and his colleagues recruited 29 adults who hadn't been diagnosed with Alzheimer's disease or any other cognitive issues. The participants took a pill that dissolves when under the tongue, releasing nitric oxide. They then lay on a mattress that caused their bodies to gently vibrate for 40 minutes, taking another pill halfway through. Blood samples revealed that their levels of a type of protein called beta-amyloid 42 increased by 35 per cent, on average, after the intervention. This protein, which usually helps neurons signal and connect to each other, misfolds and form clumps in Alzheimer's disease.